SINTX SN (Silicon Nitride)-PEEK composite combines the unique and beneficial bioactivity of silicon nitride with the familiar fit, feel, and processing properties of conventional polyetheretherketone (PEEK) polymer1,2.
This material is produced by compounding an extremely fine particulate form of SINTX MC2 Si3N4 bioceramic into an implant grade PEEK matrix. Coating delamination concerns are avoided since the bioceramic is uniformly dispersed throughout the polymer volume instead of adhered to the surface.
Subsequent forming operations produce new surfaces with the same enhanced properties as the original stock composite, giving device manufacturers design and process flexibility when working with this material.
In addition to exhibiting comparable mechanical properties to monolithic PEEK, SN-PEEK has demonstrated improved imaging properties along with resistance to biofilm formation and upregulation of bone cell activity during testing in vitro3.
Figure 2: Sample Implants
SINTX SN-PEEK composite, PEEK, and monolithic SINTX MC2 Si3N4 formed into a representative implant geometry.
Figure 3: X-ray Imaging
X-ray radiograph showing various biomaterials beneath a human hand as a demonstration of radiotranslucency (adapted from Pezzotti et al.3 ).
1. Pezzotti, G. et al., “Human Osteoblasts Grow Transitional Si/N Apatite in Quickly Osteointegrated Si3N4 Cervical Insert,” Acta Biomater., 64, 411-420, (2017).
2. Pezzotti, G. et al., “Bioactive Silicon Nitride: A New Therapeutic Material. for Osteoarthropathy,” Sci. Rep., 7 44848 (2017).
3. Pezzotti et al., Macromol. Biosci. 2018, 1800033.
4. Bock et al., J. Biomed. Mater. Res. A. 2017, 105(5):1521-1534.